Positions Available

We are looking for scientists at different career stages to fill multiple positions in our group! If you are interested in working with us but can’t find a suitable position for your career stage or goal below, feel free to reach out to Sebastian (spott@uchicago.edu) to discuss opportunities.

Postdoctoral researchers

We are looking for one or more postdoctoral researchers with interest in gene regulation, single-cell and single-molecule genomics, and/or complex diseases.

The goal of our work is to achieve a mechanistic and quantitative understanding of gene regulation in normal and diseased human cells. We combine (1) the development of multi-modal single-cell and single-molecule genomics technologies, (2) the generation of high-resolution cellular atlases of healthy and diseased tissues using single-cell methods, (3) organoid-based cell culture systems to model healthy and diseased states ex vivo (4) and CRISPR-based genetic perturbations for high-throughput functional screens of regulatory features. We have several ongoing and funded projects spanning these topics and the candidate will have an opportunity to design their own study.

The candidate should have a strong background in functional genomics, molecular biology, or computational biology. Applicants from different fields that aim to pivot their research are encouraged to apply as well.

We strive to provide a collegial and inclusive environment that nurtures scientific creativity and rigor. The University of Chicago is home to experts in single cell genomics, transcriptional regulation, and statistical genetics that offer opportunities for collaboration and supports a lively exchange of ideas.

If you have any questions regarding these positions, please don’t hesitate to contact Sebastian (spott@uchicago.edu) or apply with a cover letter describing your background and scientific motivation and your CV.


Staff scientist

We are also seeking a Staff Scientist with similar interests and a background in molecular biology, cell culture systems (organoids), and/or genomics . This position provides a unique opportunity to lead research that combines ex vivo cellular systems and cutting-edge genomics tools. The position will work with and supervise research staff in the Pott lab together with Sebastian. The candidate will be involved in data generation, analysis, and preparation scientific manuscripts.

If you have any questions please don’t hesitate to contact Sebastian (spott@uchicago.edu) or apply here.