Peer-Reviewed Publications
Selewa A., Luo K., Wasney M., Smith L., Sun X., Tang C., Eckart H., Moskowitz IP, Basu A., He X., Pott S. (2023) Single-cell genomics improves the discovery of risk variants and genes of Atrial Fibrillation. Nat Commun. 2023 Aug 17;14(1):4999. https://doi.org/10.1038/s41467-023-40505-5
Zilbauer M., James KR., Kaur M., Pott S., Li Z., Burger A., et al. (2023) A Roadmap for the Human Gut Cell Atlas. Nat Rev Gastroenterol Hepatol 2023. https://doi.org/10.1038/s41575-023-00784-1.
Rowton, M., Perez-Cervantes, C., Rydeen, A., Hur, S., Jacobs-Li, J., Deng, N., Lu, E., Guzzetta, A., Steimle, J. D., Hoffman, A., Lazarevic, S., Yang, X. H., Kim, C., Yu, S., Eckart, H., Iddir, S., Koska, M., Hanson, E., Chan, S. S., Garry, D. J., Kyba, M., Basu, A., Ikegami, K., Pott, S., Moskowitz, I. P. (2022). Hedgehog signaling activates a heterochronic gene regulatory network to control differentiation timing across lineages. Dev Cell. 2022 Sep 13:S1534-5807(22)00595-0. https://doi.org/10.1016/j.devcel.2022.08.009. Epub ahead of print. PMID: 36108627.
Mittleman, B., Pott, S., Warland, S., Barr, K., Cuevas, C., Gilad, Y. (2021). Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzees. elife, 10, e62548. https://doi.org/10.7554/eLife.62548
Guzzetta, A., Koska, M., Rowton, M., Sullivan, K. R., Jacobs-Li, J., Kweon, J., Hidalgo, H., Eckart, H., Hoffman, A. D., Back, R., Lozano, S., Moon, A. M., Basu, A., Bressan, M., Pott, S., & Moskowitz, I. P. (2020). A Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation. PNAS, 117, 27. https://doi.org/10.1073/pnas.1914167117
Mittleman, B., Pott, S., Warland, S., Zeng, T., Mu, S., Kaur, M., Gilad, Y., & Li, Y. (2020). Alternative polyadenylation mediates genetic regulation of gene expression. elife, 9, e57492. https://doi.org/10.7554/eLife.57492
Selewa, A., Dohn, R., Eckart, H., Lozano, S., Xie, B., Guachat, E., Elorbany, R., Rhodes, K., Burnett, J., Gilad, Y., Pott, S., & Basu, A. (2020). Systematic Comparison of High-throughput Single-Cell and Single-Nucleus Transcriptomes during Cardiomyocyte Differentiation. Scientific Reports, 10, 1535. https://doi.org/10.1038/s41598-020-58327-6
Chen, C., Pohl, T. J., Pott, S., & Zakian, V. A. (2019). Two Pif1 Family DNA Helicases Cooperate in Centromere Replication and Segregation in
Saccharomyces cerevisiae.
Genetics, 211(1), 105-119.
https://doi.org/10.1534/genetics.118.301710
Malik, V., Glaser, L. V., Zimmer, D., Velychko, S., Weng, M., Holzner, M., Arend, M., Chen, Y., Srivastava, Y., Veerapandian, V., Shah, Z., Esteban, M. A., Wang, H., Chen, J., Schöler, H. R., Hutchins, A. P., Meijsing, S. H., Pott, S., & Jauch, R. (2019). Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2.
Nature Communications, 10, 3477.
https://doi.org/10.1038/s41467-019-11054-7
Israel, J. W., Chappell, G. A., Simon, J. M., Pott, S., Safi, A., Lewis, L., Cotney, P., Boulos, H. S., Bodnar, W., Lieb, J. D., Crawford, G. E., Furey, T. S., & Rusyn, I. (2018). Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription.
Mammalian Genome, 29, 153-167.
https://doi.org/10.1007/s00335-018-9739-6
Chappell, G. A., Israel, J. W., Simon, J. M., Pott, S., Safi, A., Eklund, K., Sexton, K. G., Bodnar, W., Lieb, J. D., Crawford, G. E., Rusyn, I., & Furey, T. S. (2017). Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice.
Environmental Health Perspectives, 125(10), 107006-1.
https://doi.org/10.1289/EHP1937
Tran, P. L. T., Pohl, T. J., Chen, C., Chan, A., Pott, S., & Zakian, V. (2017). PIF1 family DNA helicases suppress R-loop mediated genome instability at tRNA genes.
Nature Communications, 8, 15025.
https://doi.org/10.1038/ncomms15025
Tropberger, P., Pott, S., Keller, C., Kamieniarz-Gdula, K., Caron, M., Richter, F., Li, G., Mittler, G., Liu, E. T., Bühler, M., Margueron, R., & Schneider, R. (2013). Regulation of Transcription through Acetylation of H3K122 on the Lateral Surface of the Histone Octamer.
Cell, 152(4), 859-872.
https://doi.org/10.1016/j.cell.2013.01.032
Györy, I., Boller, S., Nechanitzky, R., Mandel, E., Pott, S., Liu, E., & Grosschedl, R. (2012). Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells
. Genes & Development, 26(7), 668-682.
https://doi.org/10.1101/gad.187328.112
Pott, S., Kamrani, N. K., Bourque, G., Pettersson, S., & Liu, E. T. (2012). PPARG Binding Landscapes in Macrophages Suggest a Genome-Wide Contribution of PU.1 to Divergent PPARG Binding in Human and Mouse.
PLoS ONE, 7(10), e48102.
https://doi.org/10.1371/journal.pone.0048102
Treiber, T., Mandel, M. M., Pott, S., Györy, I., Firner, S., Liu, E. T., & Grosschedl, R. (2010). Early B Cell Factor 1 Regulates B Cell Gene Networks by Activation, Repression, and Transcription- Independent Poising of Chromatin.
Immunity, 32(5), 714-725.
https://doi.org/10.1016/j.immuni.2010.04.013
Hamza, M. S., Pott, S., Vega, V. B., Thomsen, J. S., Gopalan, S. K., Ng, P. W. P., Chiu, K. P., Pettersson, S., Wei, C. L., Ruan, Y., & Liu, E. T. (2009). De-Novo Identification of PPARɣ/RXR Binding Sites and Direct Targets during Adipogenesis.
PLoS ONE, 4(3), e4907.
https://doi.org/10.1371/journal.pone.0004907
Lundin, A., Bok, C. M., Aronsson, L., Björkholm, B., Gustafsson, J., Pott, S., Arulampalam, V., Hibberd, M., Rafter, J., & Pettersson, S. (2007). Gut flora, Toll‐like receptors and nuclear receptors: a tripartite communication that tunes innate immunity in large intestine.
Cellular Microbiology, 10(5), 1093-1103.
https://doi.org/10.1111/j.1462-5822.2007.01108.x
Commentaries